Your resume should spell out accomplishments

Tailor your resume to the position for which you are being considered

Embrace social media tools such as LinkedIn and Facebook

Maintain relationships with recruiters, even when not seeking a new position.

Treat the interview as if you are a consultant rather than a candidate

The worst mistake you can make in an interview is talking too much

Second worst mistake is not doing your homework.  Preparation is key.

Hone your ability to answer probable interview questions

Don't be afraid to ask for help--but you can't get what you don't give.